The subtelomeric region is important for chromosome recognition and pairing during meiosis

نویسندگان

  • María del Carmen Calderón
  • María-Dolores Rey
  • Adoración Cabrera
  • Pilar Prieto
چکیده

The process of meiosis results in the formation of haploid daughter cells, each of which inherit a half of the diploid parental cells' genetic material. The ordered association of homologues (identical chromosomes) is a critical prerequisite for a successful outcome of meiosis. Homologue recognition and pairing are initiated at the chromosome ends, which comprise the telomere dominated by generic repetitive sequences, and the adjacent subtelomeric region, which harbours chromosome-specific sequences. In many organisms telomeres are responsible for bringing the ends of the chromosomes close together during early meiosis, but little is known regarding the role of the subtelomeric region sequence during meiosis. Here, the observation of homologue pairing between a pair of Hordeum chilense chromosomes lacking the subtelomeric region on one chromosome arm indicates that the subtelomeric region is important for the process of homologous chromosome recognition and pairing.

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عنوان ژورنال:

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2014